Atp4b-IRES-CreERT2

品系全名

C57BL/6Smoc-Atp4bem1(IRES-CreERT2-WPRE-pA)Smoc

目录号

NM-KI-210118

品系状态

胚胎冻存

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基因信息

基因名
Atp4b

品系描述

将IRES-CreERT2-WPRE-pA插入到小鼠Atp4b基因起始密码子。与此相似的品系还有Atp4b-IRES-CreERT2(2)(NM-KI-210119),该品系的构建方式是将IRES-CreERT2插入到小鼠Atp4b基因终止密码子。
应用领域:cre工具鼠

验证数据

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Fig1. CreERT2-mediated recombination in the stomach of Atp4bCreERT2/+; Rosa26tdTomato/+ mouse. TdTomato(red) expression can be detected in the stomach of Atp4bCreERT2/+; Rosa26tdTomato/+ mouse after tamoxifen treatment. Some leakiness was detected prior to tamoxifen exposure.

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Fig2. Detection of tdTomato (red) in various tissues of  Atp4bCreERT2/+; Rosa26tdTomato/+ mice after tamoxifen treatment. Tdtomato was expressed in the glandular stomach. Tdtomato can also be detected in the pituitary, thymus, salivary glands, brown adipose tissue, spleen, pancreas, and muscle. Some leakiness was detected prior to tamoxifen exposure. TdTomato expression can not be detected in the brain, liver, lung, large intestine, small intestine, kidney or skin.


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