Nphs1-2A-CreERT2
品系全名
C57BL/6Smoc-Nphs1em1(2A-CreERT2-WPRE-pA)Smoc
目录号
NM-KI-242232
品系状态
精子冻存
基因信息
基因名
Nphs1
品系描述
验证数据

Fig1. CreERT2 mediated recombination in kidney of Nphs1CreERT2/+; Rosa26tdTomato/+ mouse.

Fig2. Detection of tdTomato(red) in various tissues of Nphs1CreERT2/+; Rosa26tdTomato/+ mouse.
Following tamoxifen induction, tdTomato expression was observed in the kidney, salivary gland, and pancreas.
No tdTomato expression was detected in the brain, heart, lung, stomach, prostate, large intestine, small intestine, reproductive system, thymus, or lymph nodes.
(89-days old, female and male) (For more detailed information please contact our technical advisor.)
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Cre-ERT2在无Tamoxifen诱导的情况下,在细胞质内处于无活性状态;当Tamoxifen诱导后,Tamoxifen的代谢产物4-OHT(雌激素类似物)与ERT结合,可使Cre-ERT2进核发挥Cre重组酶活性。
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