hIL17RA
品系全名
C57BL/6Smoc-Il17raem1(hIL17RA)Smoc
目录号
NM-HU-190049
品系状态
胚胎冻存
基因信息
基因名
IL17RA
品系描述
通过同源重组，将小鼠基因Il17ra进行人源化修饰。
应用领域：免疫治疗；肿瘤研究；药物筛选
*使用本品系发表的文献需注明: hIL17RA mice (Cat. NO. NM-HU-190049) were purchased from Shanghai Model Organisms Center, Inc..
验证数据
Fig.1 Detection of IL17RA expression in thymus by RT-PCR (male, 7-8 weeks old).
Wild type: one band at 194 bp with primers F1/R1(mIl17ra);
Homozygous: one band at 114 bp with primers F2/R2(hIL17RA).
Abbr. M, DNA marker; HO, homozygous; WT, wild type.
Fig.2 Detection of IL17RA expression by FACS.
The expression of mouse and human IL17RA were analyzed in splenic myeloid cells from 8-week-old male WT and 10-week-old male hIL17RA knockin mice.
Abbr. HO, homozygous; WT, wild type.
你也可能感兴趣
Tamoxifen诱导Cre-ERT2小鼠 使用指南
Cre-ERT2在无Tamoxifen诱导的情况下，在细胞质内处于无活性状态；当Tamoxifen诱导后，Tamoxifen的代谢产物4-OHT（雌激素类似物）与ERT结合，可使Cre-ERT2进核发挥Cre重组酶活性。
查看
