Trp73-KO

品系全名

C57BL/6JSmo-Trp73em1Smoc

目录号

NM-KO-190628

品系状态

精子冻存

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基因信息

基因名
Trp73

基因曾用名

p73; Tp73; TAp73; deltaNp73

NCBI ID

22062

MGI ID

1336991

Ensembl ID

ENSMUSG00000029026

Pubmed

Trp73

人类同源基因

TRP73

品系描述

敲除Trp73基因exon 3，建立Trp73基因敲除小鼠模型。

疾病预测

中耳炎
Otitis Media

近似模型的表型

MGI:2174786

参考文献

Yang A, Walker N, Bronson R, Kaghad M, Oosterwegel M, Bonnin J, Vagner C, Bonnet H, Dikkes P, Sharpe A, McKeon F, Caput D, p73-deficient mice have neurological, pheromonal and inflammatory defects but lack spontaneous tumours. Nature. 2000 Mar 2;404(6773):99-103

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