Cckbr-KO

品系全名

C57BL/6JSmo-Cckbrem1Smoc

目录号

NM-KO-190609

品系状态

精子冻存

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基因信息

基因名
Cckbr

品系描述

敲除Cckbr基因exon 3,建立Cckbr基因敲除小鼠模型。
应用领域:该基因编码的蛋白是一种G蛋白偶联膜受体,这种蛋白是一种B型胃泌素受体,它与硫酸盐和非硫酸盐CCK类似物都有很高的亲和力,主要存在于中枢神经系统和胃肠道。该基因的突变与结直肠和胰腺癌相关。

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