Ccr2-KO

品系全名

C57BL/6JSmo-Ccr2em1Smoc

目录号

NM-KO-190018

品系状态

活体

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基因信息

基因名
Ccr2

品系描述

敲除Ccr2基因的exon 3 区域,获得Ccr2基因敲除小鼠模型。
应用领域:免疫相关

验证数据


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图1. RT-PCR检测Ccr2-KO小鼠中Ccr2基因的表达情况。(A) 引物设计示意图;(B) 野生型小鼠(WT)中可以检测到Ccr2基因的表达,纯合子小鼠(HO)中检测不到Ccr2基因的表达。

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图2. 流式检测Ccr2-KO小鼠骨髓中CCR2的表达情况。结果显示:Ccr2-KO纯合子小鼠骨髓CD11b阳性细胞中检测不到CCR2的表达。


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图3. 流式检测Ccr2-KO小鼠脾脏中CCR2的表达情况。结果显示:Ccr2-KO纯合子小鼠脾脏CD11b阳性细胞中检测不到CCR2的表达。



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