Drd2-Flox

品系全名

C57BL/6JSmo-Drd2em1(flox)Smoc

目录号

NM-CKO-200160

品系状态

精子冻存

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基因信息

基因名
Drd2

基因曾用名

D2R; Drd-2

NCBI ID

13489

MGI ID

94924

Ensembl ID

ENSMUSG00000032259

Pubmed

Drd2

人类同源基因

DRD2

品系描述

在Drd2基因exon 2两侧分别插入loxP位点，建立Drd2基因条件性敲除小鼠模型。
应用领域：单胺GPCR和GPCR信号传导相关研究

发表文献 2篇

1. Intestinal epithelial dopamine receptor signaling drives sex-specific disease exacerbation in a mouse model of multiple sclerosis
发表年份：2023 来源杂志：IMMUNITY

2. Inhibition of astrocytic DRD2 suppresses CNS inflammation in an animal model of multiple sclerosis
发表年份：2022 来源杂志：JOURNAL OF EXPERIMENTAL MEDICINE

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