Ccr2-IRES-DTRGFP
品系全名
C57BL/6JSmo-Ccr2em1(IRES-DTRGFP)Smoc
目录号
NM-KI-210102
品系状态
活体
基因信息
基因名
Ccr2
品系描述
验证数据
图1.流式检测Ccr2-IRES-DTRGFP小鼠中GFP的表达情况。结果显示杂合子小鼠外周血CCR2和CD11b双阳性细胞中可以检测到GFP的表达。
图2.流式检测Ccr2-IRES-DTRGFP小鼠给药后CCR2/CD11b双阳性细胞和GFP阳性细胞的剔除情况。小鼠每天注射白喉毒素一次，连续注射3天，分别在停药2天和4天后检测CCR2和GFP的表达水平。结果显示停药2天后，杂合子小鼠外周血中CCR2/CD11b双阳性细胞的比例下降，同时GFP阳性细胞的表达水平也显著下降，停药4天后CCR2和CD11b双阳性细胞的表达比例恢复正常，GFP阳性细胞的表达水平也恢复正常。
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