Fos-CreERT2
品系全名
C57BL/6Smoc-Fosem1(CreERT2-SV40-pA)Smoc
目录号
NM-KI-200110
品系状态
活体
基因信息
基因名
Fos
品系描述
A CreERT2 expression cassette was knocked into the Fos gene start codon site.
应用领域：Cre recombinase tool
*使用本品系发表的文献需注明: Fos-CreERT2 mice (Cat. NO. NM-KI-200110) were purchased from Shanghai Model Organisms Center, Inc..
验证数据
Fig. 1 Detection of tdTomato (red) in different regions of brain derived from FosCreERT2/+; Rosa26tdTomato/+ mouse.
CreERT2-mediated recombination in the brian can be induced by tamoxifen after formalin injection into the mouse hind paw.
发表文献
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Tamoxifen诱导Cre-ERT2小鼠 使用指南
Cre-ERT2在无Tamoxifen诱导的情况下，在细胞质内处于无活性状态；当Tamoxifen诱导后，Tamoxifen的代谢产物4-OHT（雌激素类似物）与ERT结合，可使Cre-ERT2进核发挥Cre重组酶活性。
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