Il17a-Cre
品系全名
C57BL/6Smoc-Il17aem1(iCre-polyA(SV40))Smoc
目录号
NM-KI-200137
品系状态
活体
基因信息
基因名
IL17A
品系描述
A iCre-polyA expression cassette was knocked into the Il17a gene start codon site.
This gene encodes a pro-inflammatory cytokine that is a member of the interleukin-17 family. When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in cells expressing cre. This strain may be useful for studying autoimmune inflammatory diseases such as rheumatoid arthritis, psoriasis and multiple sclerosis.
应用领域：Cre recombinase tool; T helper cell
*使用本品系发表的文献需注明: Il17a-Cre mice (Cat. NO. NM-KI-200137) were purchased from Shanghai Model Organisms Center, Inc..
验证数据
Fig 1. Cre mediated recombination in lung of Il17aCre/+;Rosa26tdTomato/+ mouse.
Fig 2. Cre mediated recombination in mesenteric lymph nodes of Il17aCre/+;Rosa26tdTomato/+ mouse.
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