Myl2-Cre-IRES-EGFP

品系全名

C57BL/6Smoc-Myl2em1(Cre-IRES-EGFP-WPRE-polyA)Smoc

目录号

NM-KI-200224

品系状态

精子冻存

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基因信息

基因名
Myl2

品系描述

A Cre-IRES-EGFP-WPRE-polyA expression cassette was knocked into the Myl2 gene start codon site.
应用领域:These mice express cre recombinase from the Myl2 locus. This strain may be useful for studying cardiogenesis.

验证数据

NM-KI-200224 Myl2-Cre-IRES-EGFP-1.png

Fig.1 Cre-mediated recombination in the heart of Myl2Cre/+; Rosa26tdTomato/+ mouse. TdTomato(red) expression can be detected in the ventricular cardiomyocytes and few atrial cells of Myl2Cre/+; Rosa26tdTomato/+ mouse. EGFP(green) expression can not be observed.

NM-KI-200224 Myl2-Cre-IRES-EGFP-2.png

Fig. 2 Detection of tdTomato(red) and GFP(green) in various tissues of Myl2Cre/+; Rosa26tdTomato/+ mice. Cre mediated recombination can be detected in the heart, few cells of thymus, bronchus, submandibular gland, skin, kidney and choroid plexus of fourth ventricle. Tdtomato expression can not be observed in the brown fat, liver, stomach, intestine, colon, spleen, pancreas, testis and epididymis. EGFP expression can not be observed.(For more detailed information please contact our technical advisor.)


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