Acan-IRES-CreERT2

Fig. 1 CreERT2-mediated recombination in the joints of Acan^CreERT2/+; Rosa26^tdTomato/+ mouse. TdTomato(red) expression can be detected in the growth plate and articular cartilage of Acan^CreERT2/+; Rosa26^tdTomato/+ mouse after tamoxifen treatment.

Fig. 2 Detection of tdTomato(red) in various tissues of Acan^CreERT2/+; Rosa26^tdTomato/+ mice. Cre mediated recombination can be detected in the growth plate and articular cartilage after tamoxifen treatment. Tdtomato expression can be also detected in individual cells derived from the brown fat, spleen, testis, skin, skeletal muscle and cardiac valves. Tdtomato expression can not be detected in the brain, thymus, retina, lung, liver, stomach, submandibular gland, kidney, pancreas, intestine, colon, skin and myocardium. (For more detailed information please contact our technical advisor.)