Scgb1a1-IRES-CreERT2
品系全名
C57BL/6Smoc-Scgb1a1em1(IRES-CreERT2)Smoc
目录号
NM-KI-200129
品系状态
精子冻存
基因信息
基因名
Scgb1a1
品系描述
验证数据

Fig.1 CreERT2-mediated recombination in the lung of Scgb1a1CreERT2/+; Rosa26tdTomato/+ mouse. TdTomato(red) expression can be detected in the bronchial and alveolar cells of Scgb1a1CreERT2/+; Rosa26tdTomato/+ mouse after tamoxifen treatment.

Fig. 2 Detection of tdTomato(red) in various tissues of Scgb1a1CreERT2/+; Rosa26tdTomato/+ mice. CreERT2 mediated recombination can be detected in the bronchial and alveolar cells after tamoxifen treatment. TdTomato expression can not be observed in the brain, pituitary gland, heart, liver, spleen, kidney, thymus, stomach, intestine, colon, submandibular gland, ovary, uterus, skin, muscle and brown fat. (For more detailed information please contact our technical advisor.)
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Cre-ERT2在无Tamoxifen诱导的情况下,在细胞质内处于无活性状态;当Tamoxifen诱导后,Tamoxifen的代谢产物4-OHT(雌激素类似物)与ERT结合,可使Cre-ERT2进核发挥Cre重组酶活性。
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