Isl1-Cre

品系全名

C57BL/6Smoc-Isl1em1(iCre-WPRE-pA)Smoc

目录号

NM-KI-200126

品系状态

精子冻存

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基因信息

基因名
Isl1

品系描述

A iCre-WPRE-pA expression cassette was knocked into the Isl1 gene start codon site.
应用领域:Cre recombinase tool; Isl1-Cre mice express Cre recombinase under the control of the ISL1 transcription factor. It can be used for lineage tracing of Isl1 positive cells.

验证数据

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Fig. 1 Cre-mediated recombination in the retina of IslCreERT2 /+; Rosa26tdTomato/+ mouse. TdTomato(red) expression can be detected in the retinal ganglion cell layer (RGC) and inner nuclear layer (INL) of IslCre/+; Rosa26tdTomato/+ mouse.

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Fig. 2 Cre-mediated recombination in the pancreas of IslCre/+; Rosa26tdTomato/+ mouse. TdTomato(red) expression can be detected in the acinar cells and islet cells derived from IslCre/+; Rosa26tdTomato/+ mouse.

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Fig. 3 Detection of tdTomato(red) in various tissues of IslCre/+; Rosa26tdTomato/+ mice. Cre mediated recombination can be detected in the retina, pancreas, heart, brain, pituitary gland, lung, liver, stomach, submandibular gland, brown fat, kidney, intestine, colon, spleen, thymus, testis and epididymis. (For more detailed information please contact our technical advisor.)



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