Dmd-Q995X
品系全名
C57BL/6Smoc-Dmdem1(Q995X)Smoc
目录号
NM-KI-18026
品系状态
活体
基因信息
基因名
Dmd
品系描述
验证数据
Fig1 Mouse dystrophin expression is abolished due to the p.Q995X mutation.
Fig2 Histopathology of WT and MDX mice(male, 6-month-old) muscle showing less uniform muscle fibers with inflammation and clustered nuclei.
Fig3 Limb grip strength tests in MDX mice.
The assessment of limb strength in experimental mice were performed by means of grip strength meter (BIO-G53, Bioseb, France). The mice were allowed to grab the pull bar and are then gently pulled backwards. The force applied to the bar just before it loses grip was recorded as peak resistance force (expressed in grams). To reduced procedure-related variability, the tests were repeated 4 to 5 times and the average was recorded.
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