hCD3E

The endogenous mouse Cd3e gene was replaced by human CD3E gene . While hCD3E(2)(Stock No.NM-HU-210023) mice function similarly to hCD3E mice,for more detailed information please contact our technical advisor.

Fig1. The expression of human CD3E in the peripheral blood cells derived from heterozygous or homozygous humanized mice was confirmed by FACS. 

Fig2. Detection of T cell subsets in the peripheral blood cells derived from heterozygous or homozygous CD3E humanized mice.

Fig3. Detection of B and NK cells in the peripheral blood cells derived from heterozygous or homozygous CD3E humanized mice.

Fig4. In vitro T cell activation with heterozygous or homozygous CD3E humanized mice.

Fig5. Cytokine analysis of anti-human CD3E antibody treated hCD3E mice. 

The data is provided by Crownbio.