Cd2-2A-CreERT2
品系全名
C57BL/6Smoc-Cd2em1(2A-CreERT2-WPRE-pA)Smoc
目录号
NM-KI-18017
品系状态
活体
基因信息
基因名
Cd2
品系描述
A 2A-CreERT2-WPRE-pA coexpression cassette is inserted befor the stop codon of mouse Cd2 gene via homologous recombination to establish a tamoxifen inducible Cd2-CreERT2 tool stain. This strain can be used to knockout target gene in T cells and B cells after tamoxifen treatment when crossed with mice which carry loxp sites flanking target gene.
应用领域：Cre recombinase tool
*使用本品系发表的文献需注明: Cd2-2A-CreERT2 mice (Cat. NO. NM-KI-18017) were purchased from Shanghai Model Organisms Center, Inc..
验证数据
The result shows that expression pattern of RFP in T cells of Cd2-(2A-CreERT2-WPRE-pA);RFP.
你也可能感兴趣
Tamoxifen诱导Cre-ERT2小鼠 使用指南
Cre-ERT2在无Tamoxifen诱导的情况下，在细胞质内处于无活性状态；当Tamoxifen诱导后，Tamoxifen的代谢产物4-OHT（雌激素类似物）与ERT结合，可使Cre-ERT2进核发挥Cre重组酶活性。
查看
