Il2-Flox

品系全名

B6;129S-Il2tm1(flox)Smoc

目录号

NM-CKO-00108

品系状态

胚胎冻存

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基因信息

基因名
IL2

品系描述

loxp位点位于Il2基因1号至2号外显子区域两侧。若与Cre品系小鼠交配的后代可在Cre酶表达的组织中条件性敲除该基因。该品系小鼠可正常发育并生殖。Il2缺失可能导致免疫系统调节异常。
应用领域:代谢、免疫系统、造血系统等相关研究

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