hFUS
品系全名
C57BL/6Smoc-Fustm1(hFUS)Smoc
目录号
NM-HU-233955
品系状态
活体
基因信息
基因名
Fus
品系描述
利用同源重组，将小鼠Fus基因进行人源化修饰。
*使用本品系发表的文献需注明: hFUS mice (Cat. NO. NM-HU-233955) were purchased from Shanghai Model Organisms Center, Inc..
验证数据
Fig.1 Detection of FUS expression in heart, spinal cord, kidney and brain of WT C57BL/6 and HO hFUS mice by RT-PCR (female, 7 weeks old).
Wild type: only one band at 194 bp with primers F1/R1(mFus);
Homozygous: only one band at 320 bp with primers F2/R2(hFUS).
Abbr. M, DNA marker; HO, homozygous; WT, wild type.
Fig.2 Detection of human FUS expression in WT C57BL/6 and HO hFUS mice by WB (female, 7 weeks old).
Abbr. M, marker; WT, wild type; HO, Homozygous; PC, THP-1 cells.
Note. Arrow indicates expected molecular weight and asterisk indicates a nonspecific band.
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