Eno2-2A-Cre

品系全名

C57BL/6Smoc-Eno2em1(2A-iCre)Smoc

目录号

NM-KI-200012

品系状态

活体

导出PDF

基因信息

基因名
Eno2

品系描述

A 2A-iCre expression cassette was knocked into the Eno2 gene stop codon site.
应用领域:Eno2 is a highly specific marker for neuronal and peripheral neuroendocrine cells. This strain is useful in the study of human motor neuron diseases such as brain injury and spinal muscular atrophy.

验证数据

image.png

Fig. 1 Cre-mediated recombination in the brain of Eno2Cre/+; Rosa26tdTomato/+ mouse. TdTomato(red) expression can be detected in the neurons of Eno2Cre/+; Rosa26tdTomato/+ mouse. 

image.png

Fig. 2 Cre-mediated recombination in the spinal cord of Eno2Cre/+; Rosa26tdTomato/+ mouse. TdTomato(red) expression can be detected in the neurons of Eno2Cre/+; Rosa26tdTomato/+ mouse. 

image.png

Fig. 3 Detection of tdTomato(red) in various tissues of Eno2Cre/+; Rosa26tdTomato/+ mice. Tdtomato was expressed in the brain and spinal cord. TdTomato can also be detected in individual cells of the pitultary gland, testis, heart, lung, liver, stomach, submandibular gland, brown fat, kidney, pancreas, intestine, colon, spleen, thymus, muscle and skin. (For more detailed information please contact our technical advisor.)



你也可能感兴趣

Tamoxifen诱导Cre-ERT2小鼠 使用指南

Cre-ERT2在无Tamoxifen诱导的情况下,在细胞质内处于无活性状态;当Tamoxifen诱导后,Tamoxifen的代谢产物4-OHT(雌激素类似物)与ERT结合,可使Cre-ERT2进核发挥Cre重组酶活性。

查看
【小鼠大学问】基因工程小鼠的命名规则

常见的基因工程小鼠可以分为两种命名方式,包括基因定点修饰的小鼠命名,比如:敲除、敲入、点突变等等,和随机转基因的小鼠命名。

查看