Eno2-2A-Cre
品系全名
C57BL/6Smoc-Eno2em1(2A-iCre)Smoc
目录号
NM-KI-200012
品系状态
活体
基因信息
基因名
Eno2
品系描述
验证数据

Fig. 1 Cre-mediated recombination in the brain of Eno2Cre/+; Rosa26tdTomato/+ mouse. TdTomato(red) expression can be detected in the neurons of Eno2Cre/+; Rosa26tdTomato/+ mouse.

Fig. 2 Cre-mediated recombination in the spinal cord of Eno2Cre/+; Rosa26tdTomato/+ mouse. TdTomato(red) expression can be detected in the neurons of Eno2Cre/+; Rosa26tdTomato/+ mouse.

Fig. 3 Detection of tdTomato(red) in various tissues of Eno2Cre/+; Rosa26tdTomato/+ mice. Tdtomato was expressed in the brain and spinal cord. TdTomato can also be detected in individual cells of the pitultary gland, testis, heart, lung, liver, stomach, submandibular gland, brown fat, kidney, pancreas, intestine, colon, spleen, thymus, muscle and skin. (For more detailed information please contact our technical advisor.)
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Cre-ERT2在无Tamoxifen诱导的情况下,在细胞质内处于无活性状态;当Tamoxifen诱导后,Tamoxifen的代谢产物4-OHT(雌激素类似物)与ERT结合,可使Cre-ERT2进核发挥Cre重组酶活性。
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