hANGPTL3(5)
品系全名
C57BL/6Smoc-Angptl3tm3(hANGPTL3)Smoc
目录号
NM-HU-230047
品系状态
活体
基因信息
基因名
Angptl3
品系描述
The endogenous mouse Angptl3 gene was replaced by human ANGPTL3 gene.
*使用本品系发表的文献需注明: hANGPTL3(5) mice (Cat. NO. NM-HU-230047) were purchased from Shanghai Model Organisms Center, Inc..
验证数据
Fig.1 Detection of ANGPTL3 expression in liver of HO hANGPTL3(5) mice by RT-PCR. （male， 8wks）
Wild type: only one band at 155 bp with primers F1/R1(mAngptl3);
Homozygous: only one band at 155 bp with primers F2/R2(hANGPTL3).
Abbr. M, DNA marker; HO, homozygous; WT, wild type.
Fig.2 Detection of human ANGPTL3 expression in serum by ELISA (n=3).
Abbr. HO, homozygous; WT, wild type; N.D. not detected.
Table.1 Blood biochemical test of WT mice and hANGPTL3(5) knockin mice.
Values are expressed as mean±SEM.
Abbr. HO, homozygous; WT, wild type.
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