hIL1A
品系全名
C57BL/6Smoc-Il1atm1(hIL1A)Smoc
目录号
NM-HU-215071
品系状态
胚胎冻存
基因信息
基因名
Il1a
品系描述
The endogenous mouse Il1a gene was replaced by human IL1A gene.
*使用本品系发表的文献需注明: hIL1A mice (Cat. NO. NM-HU-215071) were purchased from Shanghai Model Organisms Center, Inc..
验证数据
Fig.1 Detection of IL1A expression in spleen and lung by RT-PCR.
Wild type: only one band at 324 bp with primers F1/R1(mIl1a);
Homozygous: only one band at 265 bp with primers F2/R2(hIL1A).
Abbr. M, DNA marker; HO, homozygous; WT, wild type.
Fig.2 Detection of hIL1A expression in bone marrow by ELISA (n=3).
Abbr. WT, wild type; HO, homozygous; N.D. not detected.
Note. Monocytes derived from bone marow were stimulated with LPS in vitro for 24h.
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