Ccr2-IRES-DTRGFP

品系全名

C57BL/6Smoc-Ccr2em1(IRES-DTRGFP)Smoc

目录号

NM-KI-210102

品系状态

活体

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基因信息

基因名
Ccr2

基因曾用名

Ckr2; Ccr2a; Ccr2b; Ckr2a; Ckr2b; mJe-r; Cmkbr2; Cc-ckr-2

染色体位置

9

NCBI ID

12772

MGI ID

106185

Ensembl ID

ENSMUSG00000049103

Pubmed

Ccr2

人类同源基因

CCR2

品系描述

IRES-DTRGFP expression cassette was knocked into the Ccr2 gene .

验证数据

5.png

Fig1. Analysis of GFP expression in the Ccr2-IRES-DTRGFP mice by FACS. The expression of GFP could be detected in CCR2+ and CD11b+ cells in peripheral blood of the heterozygous KI mice.

6.png

Fig2. Analysis of CCR2+/CD11b+ cells proportion and GFP level in Ccr2-IRES-DTRGFP mice by FACS. The heterozygous KI mice were treated with DT (qd x 3 days).After 2 days of drug withdrawal, the proportion of CCR2+ and CD11b+ cells in the peripheral blood were decreased, and the level of GFP positive cells also decreased. After 4 days of drug withdrawal, the proportion of CCR2+ and CD11b+ cells returned to normal, and the level of GFP positive cells also returned to normal.

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