Il7r-Cre
品系全名
C57BL/6Smoc-Il7rem1(Cre-Wpre-pA)Smoc
目录号
NM-KI-200306
品系状态
活体
基因信息
基因名
Il7r
品系描述
验证数据

Fig. 1 Cre-mediated recombination in spleen of Il7rCre/+; Rosa26tdTomato/+ mouse.
Detection of tdTomato (red) in the red and white pulp of spleen drived from Il7rCre/+; Rosa26tdTomato/+ mouse.

Fig. 2: Detection of tdTomato (red) in various tissues of Il7rCre/+; Rosa26tdTomato/+ mice. Cre-mediated recombination can be detected in some cells of spleen, brain, pituitary gland, submandibular gland, retina, lung and pancreas. Besides, tdTomato expression can also be observed in myocardial cells and skeletal muscle cells.(For more detailed information please contact our technical advisor.)
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Cre-ERT2在无Tamoxifen诱导的情况下,在细胞质内处于无活性状态;当Tamoxifen诱导后,Tamoxifen的代谢产物4-OHT(雌激素类似物)与ERT结合,可使Cre-ERT2进核发挥Cre重组酶活性。
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