Gja1-2A-DreERT2

品系全名

C57BL/6Smoc-Gja1em1(2A-DreERT2）Smoc

目录号

NM-KI-200026

品系状态

精子冻存

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基因信息

基因名
Gja1

基因曾用名

Cx43; Npm1; Cnx43; Gja-1; AU042049; AW546267; Cx43alpha1; connexin43

NCBI ID

14609

MGI ID

95713

Ensembl ID

ENSMUSG00000050953

Pubmed

Gja1

人类同源基因

GJA1

品系描述

A 2A-DreERT2 expression cassette was knocked into the Gja1 gene stop codon site via CRISPR/Cas9 mediated recombination.
应用领域：Dre recombinase tool

验证数据

image.png

Fig.1 DreERT2-mediated recombination in the adipose tissue of Gja1DreERT2/+；R26tdTomato/+ mouse. TdTomato (red) expression can be detected in the adipose tissue after tamoxifen treatment. Connexin 43 (Cx43, encoded by Gja1, green) is a cell-cell communication gap junction protein expressed in adipose tissue. (Documented in the following reference.)


发表文献

A Suite of New Dre-recombinase Drivers Markedly Expands the Ability to Perform Intersectional Genetic Targeting
来源杂志：CELL STEM CELL

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