Pax7-2A-DreERT2
品系全名
C57BL/6Smoc-Pax7em1(2A-DreERT2)Smoc
目录号
NM-KI-190124
品系状态
胚胎冻存
基因信息
基因名
Pax7
品系描述
验证数据

Fig. 1 DreERT2-mediated recombination in the brain and muscle of Pax7DreERT2/+; Rosa26RFP/+ mouse.
RFP+ cells (red) were colocalized with GFP+ cells (green) in the brain and muscle of Pax7DreERT2/+; Rosa26RFP/+ mouse after tamoxifen treatment. However, the expression of RFP by induced dre with Pax7DreERT2/+ was less effective in the muscle. (Collaborated with Prof. Zhou bin’s group from Center for Excellence in Molecular Cell Science, CAS)

Fig. 2: Detection of RFP in various tissues of Pax7DreERT2/+; Rosa26RFP/+ mice. (For more detailed information please contact our technical advisor.) (Collaborated with Prof. Zhou bin’s group from Center for Excellence in Molecular Cell Science, CAS)
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Cre-ERT2在无Tamoxifen诱导的情况下,在细胞质内处于无活性状态;当Tamoxifen诱导后,Tamoxifen的代谢产物4-OHT(雌激素类似物)与ERT结合,可使Cre-ERT2进核发挥Cre重组酶活性。
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