Rbfox3-2A-DreERT2
品系全名
C57BL/6Smoc-Rbfox3em1(2A-DreERT2-WPRE-pA)Smoc
目录号
NM-KI-190103
品系状态
精子冻存
基因信息
基因名
Rbfox3
品系描述
A 2A-DreERT2-WPRE-pA expression cassette was knocked into the Rbfox3 gene stop codon site.
应用领域：Dre recombinase tool
*使用本品系发表的文献需注明: Rbfox3-2A-DreERT2 mice (Cat. NO. NM-KI-190103) were purchased from Shanghai Model Organisms Center, Inc..
验证数据
Fig.1 DreERT2-mediated recombination in the brain of Rbfox3DreERT2/+；R26tdTomato/+ mouse. TdTomato (red) expression can be detected in the brain after tamoxifen treatment. NeuN(green) is a well-recognized "marker" that is detected in mature neurons. (Documented in the following reference.)
发表文献
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Tamoxifen诱导Cre-ERT2小鼠 使用指南
Cre-ERT2在无Tamoxifen诱导的情况下，在细胞质内处于无活性状态；当Tamoxifen诱导后，Tamoxifen的代谢产物4-OHT（雌激素类似物）与ERT结合，可使Cre-ERT2进核发挥Cre重组酶活性。
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