hIl5
品系全名
C57BL/6Smoc-Il5tm3(hIL5)Smoc
目录号
NM-HU-190001
品系状态
胚胎冻存
基因信息
基因名
IL5
品系描述
This IL5 humanized mouse model was established by replacing the mouse Il5 gene coding exons and introns with the human TLR9 corresponding sequence by homologous recombination.
应用领域：Immune-related
*使用本品系发表的文献需注明: hIl5 mice (Cat. NO. NM-HU-190001) were purchased from Shanghai Model Organisms Center, Inc..
验证数据
Fig1. Detection of IL-5 expression in thymus by RT-PCR. Wild type: only one band at 206 bp with primers F1/R1(mIl-5);Homozygous: only one band at 207 bp with primers F2/R2(hIL-5); Abbr.. M, DNA marker; HO, homozygous; HE, heterozygous; WT, wild type.
Fig 2. Expression of human IL5 in the Serum of IL5-HU homozygous mice is detected by Elisa.
Fig 3. Expression of murine IL5 in the Serum of IL5-HU homozygous mice is detected by Elisa.
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