Lrat-2A-Cre

品系全名

C57BL/6Smoc-Lratem1(2A-Cre)Smoc

目录号

NM-KI-190097

品系状态

活体

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基因信息

基因名
Lrat

基因曾用名

AI449251; 1300010A18Rik

NCBI ID

79235

MGI ID

1891259

Ensembl ID

ENSMUSG00000028003

Pubmed

Lrat

人类同源基因

LRAT

品系描述

A 2A-Cre expression cassette was knocked into the Lrat gene stop codon site.
应用领域：Cre recombinase tool

验证数据

lrat-1.png

Fig1. Expression Pattern of tdTomato in LratCre/+ ; Rosa26tdTomato/+ mice.

Cre mediated recombination in  liver nonparenchymal cells of LratCre/+ ; Rosa26tdTomato/+ mice. This strain represents an effective tool for generating liver nonparenchymal cells specific targeted mutants.

lrat-2.png

Fig2. Validation of  tdTomato  expression  by fluorescence assay.

The  liver nonparenchymal cells of Lrat-Cre mice were detected by fluorescence.

image.png

Fig. 3 Detection of tdTomato(red) in various tissues of LratCre/+; Rosa26tdTomato/+ mice. Cre-mediated recombination can be detected in some cells of the heart, liver, lung, stomach, uterus, colon, intestine, muscle and spleen. Tdtomato can not be detected in the retina, brown fat, submandibular gland or thymus. (For more detailed information please contact our technical advisor.)


发表文献

Aberrant iron distribution via hepatocyte-stellate cell axis drives liver lipogenesis and fibrosis
来源杂志：Cell Metabolism

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