hGPNMB
品系全名
C57BL/6Smoc-Gpnmbtm1(hGPNMB)Smoc
目录号
NM-HU-231635
品系状态
活体
基因信息
基因名
Gpnmb
品系描述
利用同源重组，将小鼠Gpnmb基因进行人源化修饰。
*使用本品系发表的文献需注明: hGPNMB mice (Cat. NO. NM-HU-231635) were purchased from Shanghai Model Organisms Center, Inc..
验证数据
Fig.1 Detection of GPNMB expression in bladder of WT C57BL/6 mice (female, 8-10 weeks old) and hGPNMB knockin mice (female, 7 weeks old) by RT-PCR.
Wild type: only one band at 186 bp with primers F1/R1(mGPNMB);
Homozygous: only one band at 139 bp with primers F2/R2(hGPNMB).
Abbr. M, DNA marker; HO, homozygous; WT, wild type.
Fig.2 Detection of human GPNMB expression in WT C57BL/6 mice (male, 8-10 weeks old) and hGPNMB knockin mice (male, 14 weeks old) by WB.
Abbr. M, marker; WT, wild type; HO, Homozygous; PC, positive control, B16F10 cells.
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