C57BL/6

品系全名

C57BL/6

目录号

SM-001

品系状态

活体

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品系描述

是第一个完成基因组测序的小鼠品系,毛色为黑色,被认作"标准"的近交系,为许多突变基因提供遗传背景。具有品系稳定、易于繁殖,应激反应均一,试验结果精度高等特点。

验证数据

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图1.C57BL/6小鼠生长曲线(n=840)。

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图2.C57BL/6小鼠血常规检测。



发表文献 32篇

1. A novel whole cancer cell vaccine based on modified β-glucan elicits robust anti-tumor immunity
发表年份:2026 来源杂志:Theranostics

2. Targeting senescent EGR1+ B cells enhances immunotherapy efficacy in esophageal squamous cell carcinoma
发表年份:2026 来源杂志:Cell Reports Medicine

3. Ganoderma lucidum polysaccharide ameliorates cancer cachexia with enhanced efficacy in aged group by reprogramming arginine metabolism to modulate Treg formation
发表年份:2026 来源杂志:CANCER LETTERS

4. Post-traumatic stress disorder impairs CD8+ T cell-dependent anti-tumor immune responses by downregulating thiamine
发表年份:2026 来源杂志:Cell Communication and Signaling

5. Exposure to paraben in early gestational period: Impact on placental estrogen biosynthesis and fetal growth restriction
发表年份:2026 来源杂志:ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

6. GABA induces myokine irisin release from skeletal muscle
发表年份:2026 来源杂志:LIFE SCIENCES

7. Pyruvate kinase M2 -mediated histone lactylation alters three-dimensional genomic architecture in polycystic ovary syndrome
发表年份:2025 来源杂志:Signal Transduction and Targeted Therapy

8. Inhibiting Liver-Derived C3 Protein Rescues Anesthesia/Surgery-Induced Cognitive Impairment, Synaptic Disorders, and Microglial Phagocytosis
发表年份:2025 来源杂志:Advanced Science

9. High-Resolution Multiplexed Sequencing of Single-Cell Full-length Transcriptome Via Combinational Barcoded Tn5 Transposon Insertion
发表年份:2025 来源杂志:Advanced Science

10. Glycyrrhiza polysaccharide-adjuvanted liposomal vaccine potentiates tumor immunotherapy through lymph node-targeted modulation of the DC-T cell axis
发表年份:2025 来源杂志:JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

11. Targeting the ac4C ‘Writer’ NAT10 enhances pancreatic cancer immunotherapy via dual modulation of CD8+ T cells and tumor cells
发表年份:2025 来源杂志:Cell Death & Disease

12. Extracellular vesicles for delivery of functional telomerase
发表年份:2025 来源杂志:Cell Communication and Signaling

13. An injectable cisplatin hydrogel effectively suppresses tumors while preserving anti-infective immunity
发表年份:2025 来源杂志:MATERIALS & DESIGN

14. The Artemisia argyi oil reduces high-fat diet-induced obesity by enhancing thermogenesis in brown adipose tissue
发表年份:2025 来源杂志:npj Science of Food

15. Cancer-associated adipocytes mediate CD8+T cell dysfunction via FGF21-driven lipolysis
发表年份:2025 来源杂志:Cell Reports

16. Activated T cells degrade extracellular proteins to enhance effector functions
发表年份:2025 来源杂志:Cell Reports

17. Therapeutic efficacy of Sanhuang Xiexin decoction on atopic dermatitis via suppressing STAT3 signaling
发表年份:2025 来源杂志:JOURNAL OF ETHNOPHARMACOLOGY

18. Sex-dimorphic reprogramming of fetal mouse brain development by maternal estradiol excess
发表年份:2025 来源杂志:Biology of Sex Differences

19. α-Klotho Supplementation Mitigates Cumulative Exercise-Induced Fatigue via Coordinated NRF2-Mediated Antioxidant Defense and AKT/GS-Driven Hepatic Glycogen Supercompensation in Mice
发表年份:2025 来源杂志:INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

20. Therapeutic Efficacy and Mechanistic Insights of Umbilical Cord Mesenchymal Stem Cell-Derived Exosomes in Chemotherapy-Induced Oral Mucositis
发表年份:2025 来源杂志:JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY

21. Integrating global burden of disease analysis and single-cell omics identifies ANTXR2 as a potential diagnostic biomarker for AML in China
发表年份:2025 来源杂志:INTERNATIONAL IMMUNOPHARMACOLOGY

22. Andrographolide inhibits the upregulation of SLC19A3 to block the adipogenic differentiation of adipose-derived stem cells
发表年份:2025 来源杂志:iScience

23. Optimization of thrombopoietin mimetic peptide fusion proteins with albumin-binding domain for enhanced bioactivity and extended half-life
发表年份:2025 来源杂志:Scientific Reports

24. Blockade of CD47 signaling improves ferroptosis of lung cancer cells via activating Nrf2/FPN signaling
发表年份:2025 来源杂志:CELLULAR SIGNALLING

25. Hepatic stellate cells shape the ECM-disorganized and immunosuppressive microenvironment via CCL11/CCR3 axis in lenvatinib-treated hepatocellular carcinoma
发表年份:2025 来源杂志:CELLULAR SIGNALLING

26. Optical characterization of ocular collagen microstructure and anisotropy in animal and human eyes
发表年份:2025 来源杂志:Biomedical Optics Express

27. Asiaticoside protects against PDF-induced peritoneal fibrosis via suppression of AhR/Nrf2-mediated MMT and oxidative stress
发表年份:2025 来源杂志:NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

28. A multi-omics landscape of programmed cell death in acetaminophen-induced acute kidney injury
发表年份:2025 来源杂志:RENAL FAILURE

29. USP18 promote tumor immune evasion in pancreatic cancer through enhancing autolysosome-mediated degradation of MHC-I
发表年份:2025 来源杂志:American Journal of Cancer Research

30. Helicobacter pylori Lipopolysaccharide Upregulates MDM2 via the TLR4/MAPK/AP-1 Pathway to Promote Gastric Cancer Progression
发表年份:2025 来源杂志:DIGESTIVE DISEASES AND SCIENCES

31. Protocol for co-culture of primary neurons and organotypic hippocampal brain slices from mice
发表年份:2025 来源杂志:STAR Protocols

32. Extending dual-targeting upper-limit in liposomal delivery of lithospermic acid B for Alzheimer's mitochondrial revitalization
发表年份:2024 来源杂志:JOURNAL OF CONTROLLED RELEASE

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