模型资源
C57BL/6
品系全名
C57BL/6
目录号
SM-001
品系状态
活体
品系描述
验证数据

图1.C57BL/6小鼠生长曲线(n=840)。

图2.C57BL/6小鼠血常规检测。
发表文献 81篇
1.
Spatially Defined DNA Origami Cell Engagers for T and Natural Killer Cell-Mediated Immune Modulation
发表年份:2026
来源杂志:ACS Nano
2.
A novel whole cancer cell vaccine based on modified β-glucan elicits robust anti-tumor immunity
发表年份:2026
来源杂志:Theranostics
3.
3D-cultured hUC-MSC-derived exosomes as macrophage mediators to suppress cholestatic fibrosis in mice via miR-1291–mediated multi-targeted pathways
发表年份:2026
来源杂志:CHEMICAL ENGINEERING JOURNAL
4.
Targeting senescent EGR1+ B cells enhances immunotherapy efficacy in esophageal squamous cell carcinoma
发表年份:2026
来源杂志:Cell Reports Medicine
5.
Ganoderma lucidum polysaccharide ameliorates cancer cachexia with enhanced efficacy in aged group by reprogramming arginine metabolism to modulate Treg formation
发表年份:2026
来源杂志:CANCER LETTERS
6.
Post-traumatic stress disorder impairs CD8+ T cell-dependent anti-tumor immune responses by downregulating thiamine
发表年份:2026
来源杂志:Cell Communication and Signaling
7.
Long-term sucralose exposure accelerates ovarian aging via gut microbiota dysbiosis
发表年份:2026
来源杂志:npj Science of Food
8.
Law-NQO1 redox boosts the pentose phosphate pathway to confer stem-like properties and antitumor durability in effector CD8+ T cells
发表年份:2026
来源杂志:Cell Chemical Biology
9.
Glioma Cell Membrane–Coated CaCO3 Nanoparticles for Localized Postoperative Chemo–Calcium Overload Therapy to Prevent Glioma Recurrence
发表年份:2026
来源杂志:International Journal of Nanomedicine
10.
Exposure to paraben in early gestational period: Impact on placental estrogen biosynthesis and fetal growth restriction
发表年份:2026
来源杂志:ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
11.
NOTCH3 attenuates cytotoxicity via RBPJ-dependent PVR upregulation to influence immunotherapy outcomes in colorectal cancer
发表年份:2026
来源杂志:Frontiers in Immunology
12.
Botulinum Neurotoxin Type A1 Alleviates Bleomycin-induced Skin Fibrosis by Inhibiting PI3K-Akt Pathway and Associated Cell Cycle and Proliferation
发表年份:2026
来源杂志:JOURNAL OF INVESTIGATIVE DERMATOLOGY
13.
Eupalinolide B ameliorates liver fibrosis by targeting PKCα to suppress the AKT/mTOR axis in hepatic stellate cells
发表年份:2026
来源杂志:JOURNAL OF ETHNOPHARMACOLOGY
14.
GABA induces myokine irisin release from skeletal muscle
发表年份:2026
来源杂志:LIFE SCIENCES
15.
ROS-responsive diselenide exosomes restores mitophagy to resolve sterile inflammation in liver IRI
发表年份:2026
来源杂志:EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
16.
ACSL4 Inhibition by AS-252424 Protects Visual Function by Suppressing RGC Ferroptosis After Retinal Ischemia Reperfusion Injury
发表年份:2026
来源杂志:MOLECULAR NEUROBIOLOGY
17.
Transcriptional Heterogeneity of Cardiac Remodeling Between Type 1 and Type 2 Diabetes
发表年份:2026
来源杂志:Biomedicines
18.
Lycium barbarum Polysaccharide Alleviates Renal Damage in Mouse Sepsis by Regulating M1/M2 Macrophage Polarization
发表年份:2026
来源杂志:Food Science & Nutrition
19.
Phenothiazine alleviates cisplatin-mediated acute kidney injury by inhibiting ferroptosis
发表年份:2026
来源杂志:CELL AND TISSUE RESEARCH
20.
Loss of hepaCAM inhibits cholesterol biosynthesis and impairs learning and memory in mice
发表年份:2026
来源杂志:BRAIN RESEARCH
21.
Pyruvate kinase M2 -mediated histone lactylation alters three-dimensional genomic architecture in polycystic ovary syndrome
发表年份:2025
来源杂志:Signal Transduction and Targeted Therapy
22.
Inhibiting Liver-Derived C3 Protein Rescues Anesthesia/Surgery-Induced Cognitive Impairment, Synaptic Disorders, and Microglial Phagocytosis
发表年份:2025
来源杂志:Advanced Science
23.
High-Resolution Multiplexed Sequencing of Single-Cell Full-length Transcriptome Via Combinational Barcoded Tn5 Transposon Insertion
发表年份:2025
来源杂志:Advanced Science
24.
Glycyrrhiza polysaccharide-adjuvanted liposomal vaccine potentiates tumor immunotherapy through lymph node-targeted modulation of the DC-T cell axis
发表年份:2025
来源杂志:JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
25.
Targeting the ac4C ‘Writer’ NAT10 enhances pancreatic cancer immunotherapy via dual modulation of CD8+ T cells and tumor cells
发表年份:2025
来源杂志:Cell Death & Disease
26.
Extracellular vesicles for delivery of functional telomerase
发表年份:2025
来源杂志:Cell Communication and Signaling
27.
An injectable cisplatin hydrogel effectively suppresses tumors while preserving anti-infective immunity
发表年份:2025
来源杂志:MATERIALS & DESIGN
28.
The Artemisia argyi oil reduces high-fat diet-induced obesity by enhancing thermogenesis in brown adipose tissue
发表年份:2025
来源杂志:npj Science of Food
29.
Activated T cells degrade extracellular proteins to enhance effector functions
发表年份:2025
来源杂志:Cell Reports
30.
Cancer-associated adipocytes mediate CD8+T cell dysfunction via FGF21-driven lipolysis
发表年份:2025
来源杂志:Cell Reports
31.
Therapeutic efficacy of Sanhuang Xiexin decoction on atopic dermatitis via suppressing STAT3 signaling
发表年份:2025
来源杂志:JOURNAL OF ETHNOPHARMACOLOGY
32.
Sex-dimorphic reprogramming of fetal mouse brain development by maternal estradiol excess
发表年份:2025
来源杂志:Biology of Sex Differences
33.
α-Klotho Supplementation Mitigates Cumulative Exercise-Induced Fatigue via Coordinated NRF2-Mediated Antioxidant Defense and AKT/GS-Driven Hepatic Glycogen Supercompensation in Mice
发表年份:2025
来源杂志:INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
34.
Therapeutic Efficacy and Mechanistic Insights of Umbilical Cord Mesenchymal Stem Cell-Derived Exosomes in Chemotherapy-Induced Oral Mucositis
发表年份:2025
来源杂志:JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY
35.
Integrating global burden of disease analysis and single-cell omics identifies ANTXR2 as a potential diagnostic biomarker for AML in China
发表年份:2025
来源杂志:INTERNATIONAL IMMUNOPHARMACOLOGY
36.
Andrographolide inhibits the upregulation of SLC19A3 to block the adipogenic differentiation of adipose-derived stem cells
发表年份:2025
来源杂志:iScience
37.
Optimization of thrombopoietin mimetic peptide fusion proteins with albumin-binding domain for enhanced bioactivity and extended half-life
发表年份:2025
来源杂志:Scientific Reports
38.
Blockade of CD47 signaling improves ferroptosis of lung cancer cells via activating Nrf2/FPN signaling
发表年份:2025
来源杂志:CELLULAR SIGNALLING
39.
Hepatic stellate cells shape the ECM-disorganized and immunosuppressive microenvironment via CCL11/CCR3 axis in lenvatinib-treated hepatocellular carcinoma
发表年份:2025
来源杂志:CELLULAR SIGNALLING
40.
Optical characterization of ocular collagen microstructure and anisotropy in animal and human eyes
发表年份:2025
来源杂志:Biomedical Optics Express
41.
Asiaticoside protects against PDF-induced peritoneal fibrosis via suppression of AhR/Nrf2-mediated MMT and oxidative stress
发表年份:2025
来源杂志:NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY
42.
A multi-omics landscape of programmed cell death in acetaminophen-induced acute kidney injury
发表年份:2025
来源杂志:RENAL FAILURE
43.
USP18 promote tumor immune evasion in pancreatic cancer through enhancing autolysosome-mediated degradation of MHC-I
发表年份:2025
来源杂志:American Journal of Cancer Research
44.
Helicobacter pylori Lipopolysaccharide Upregulates MDM2 via the TLR4/MAPK/AP-1 Pathway to Promote Gastric Cancer Progression
发表年份:2025
来源杂志:DIGESTIVE DISEASES AND SCIENCES
45.
Protocol for co-culture of primary neurons and organotypic hippocampal brain slices from mice
发表年份:2025
来源杂志:STAR Protocols
46.
Lighting up arginine metabolism reveals its functional diversity in physiology and pathology
发表年份:2024
来源杂志:Cell Metabolism
47.
2D Differential Metallic Immunopotentiators Drive High Diversity and Capability of Antigen-specific Immunity Against Tumor
发表年份:2024
来源杂志:Advanced Science
48.
Drug evaluation platform based on non-destructive and real-time in situ organoid fate state monitoring by graphene field-effect transistor
发表年份:2024
来源杂志:CHEMICAL ENGINEERING JOURNAL
49.
A spatiotemporal transcriptomic atlas of mouse placentation
发表年份:2024
来源杂志:Cell Discovery
50.
TIPE2 protein restrains invariant NKT activation and protects against immune-mediated hepatitis in mice
发表年份:2024
来源杂志:HEPATOLOGY
51.
Extending dual-targeting upper-limit in liposomal delivery of lithospermic acid B for Alzheimer's mitochondrial revitalization
发表年份:2024
来源杂志:JOURNAL OF CONTROLLED RELEASE
52.
PPARα suppresses growth of hepatocellular carcinoma in a high-fat diet context by reducing neutrophil extracellular traps release
发表年份:2024
来源杂志:JHEP Reports
53.
Microglia LILRB4 upregulation reduces brain damage after acute ischemic stroke by limiting CD8+ T cell recruitment
发表年份:2024
来源杂志:Journal of Neuroinflammation
54.
Advanced paternal age exacerbates neuroinflammation in offspring via m6A modification-mediated intergenerational inheritance
发表年份:2024
来源杂志:Journal of Neuroinflammation
55.
Absence of Langerhans cells resulted in over-influx of neutrophils and increased bacterial burden in skin wounds
发表年份:2024
来源杂志:Cell Death & Disease
56.
SSRI antidepressant citalopram reverses the Warburg effect to inhibit hepatocellular carcinoma by directly targeting GLUT1
发表年份:2024
来源杂志:Cell Reports
57.
Osteocalcin-expressing neutrophils from skull bone marrow exert immunosuppressive and neuroprotective effects after TBI
发表年份:2024
来源杂志:Cell Reports
58.
IGSF9 promotes tumor invasion and metastasis through GSK-3β/β-catenin mediated EMT in lung cancer
发表年份:2024
来源杂志:NEOPLASIA
59.
MRG15 promotes cell apoptosis through inhibition of mitophagy in hyperlipidemic acute pancreatitis
发表年份:2024
来源杂志:APOPTOSIS
60.
HMGB2 promotes smooth muscle cell proliferation through PPAR-γ/PGC-1α pathway-mediated glucose changes in aortic dissection
发表年份:2024
来源杂志:ATHEROSCLEROSIS
61.
The natural flavonoid pinocembrin shows antithrombotic activity and suppresses septic thrombosis
发表年份:2024
来源杂志:INTERNATIONAL IMMUNOPHARMACOLOGY
62.
Betaine alleviates nonalcoholic fatty liver disease (NAFLD) via a manner involving BHMT/FTO/m6A/ PGC1α signaling
发表年份:2024
来源杂志:JOURNAL OF NUTRITIONAL BIOCHEMISTRY
63.
F-Box and WD repeat domain containing 7 induces infectious osteomyelitis by regulating MYB stability and ubiquitination
发表年份:2024
来源杂志:SCANDINAVIAN JOURNAL OF IMMUNOLOGY
64.
Full-length circRNA sequencing method using low-input RNAs and profiling of circRNAs in MPTP-PD mice on a nanopore platform
发表年份:2024
来源杂志:ANALYST
65.
SIRT5 safeguards against T-2 toxin induced liver injury by repressing iron accumulation, oxidative stress, and the activation of NLRP3 inflammasome
发表年份:2024
来源杂志:TOXICOLOGY AND APPLIED PHARMACOLOGY
66.
Docosahexaenoic acid insufficiency impairs placental angiogenesis by repressing the methylene-bridge fatty acylation of AKT in preeclampsia
发表年份:2024
来源杂志:PLACENTA
67.
Neuron-specific deficiency of autophagy increases neuronal loss in traumatic brain injury
发表年份:2024
来源杂志:PNAS Nexus
68.
Establishment of a Mouse Model for Porokeratosis Due to Mevalonate Diphosphate Decarboxylase Deficiency
发表年份:2024
来源杂志:SKIN RESEARCH AND TECHNOLOGY
69.
Identification of Periosteal Osteogenic Progenitors in Jawbone
发表年份:2022
来源杂志:JOURNAL OF DENTAL RESEARCH
70.
Identification of circular RNA biomarkers for Pien Tze Huang treatment of CCl4‑induced liver fibrosis using RNA‑sequencing
发表年份:2022
来源杂志:Molecular Medicine Reports
71.
Methyl Diet Enhanced Sepsis-Induced Mortality Through Altering Gut Microbiota
发表年份:2021
来源杂志:Journal of Inflammation Research
72.
Effect of κ-carrageenan on glucolipid metabolism and gut microbiota in high-fat diet-fed mice
发表年份:2021
来源杂志:Journal of Functional Foods
73.
Activation of Gonadotropin-releasing Hormone Receptor Impedes the Immunosuppressive Activity of Decidual Regulatory T Cells via Deactivating the Mechanistic Target of Rapamycin Signaling
发表年份:2021
来源杂志:IMMUNOLOGICAL INVESTIGATIONS
74.
An electrochemical sensor for bacterial lipopolysaccharide detection based on dual functional Cu2+-modified metal–organic framework nanoparticles
发表年份:2020
来源杂志:MICROCHIMICA ACTA
75.
Exercise Preconditioning Protects against Acute Cardiac Injury Induced by Lipopolysaccharide Through General Control Nonderepressible 2 Kinase
发表年份:2020
来源杂志:International Heart Journal
76.
P11 Loss-of-Function is Associated with Decreased Cell Proliferation and Neurobehavioral Disorders in Mice
发表年份:2019
来源杂志:International Journal of Biological Sciences
77.
Regulation of the NLRP3 inflammasome and macrophage pyroptosis by the p38 MAPK signaling pathway in a mouse model of acute lung injury
发表年份:2018
来源杂志:Molecular Medicine Reports
78.
Contradictory effects of mitochondria- and non-mitochondria-targeted antioxidants on hepatocarcinogenesis by altering DNA repair in mice
发表年份:2017
来源杂志:HEPATOLOGY
79.
SIRT3 prevents angiotensin II-induced renal tubular epithelial-mesenchymal transition by ameliorating oxidative stress and mitochondrial dysfunction
发表年份:2017
来源杂志:MOLECULAR AND CELLULAR ENDOCRINOLOGY
80.
Cytotoxic T lymphocyte antigen 4 decreases humoral and cellular immunity by adenovirus to enhance target GFP gene transfer in C57BL/6 mice
发表年份:2015
来源杂志:IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY
81.
Establishment of a transgenic mouse model of corneal dystrophy overexpressing human BIGH3
发表年份:2013
来源杂志:INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE
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