HLA-A11.1/B2M(M-NSG)

品系全名

NOD.Cg-PrkdcscidIl2rgem1B2mtm1(hB2M-linker-HLA-A*1101/H2-D1)Smoc

目录号

NM-HU-252346

品系状态

活体

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基因信息

基因名
B2M

品系描述

利用同源重组,将小鼠B2m基因进行人源化修饰。

验证数据

image.png

Fig.1 Detection of hB2M and HLA-A,B,C expression on leukocytes in blood of WT M-NSG mice and F0(+) HLA-A11.1/B2M(M-NSG) mice by FACS.

Leukocytes were collected from wild-type M-NSG mice (male, 8 weeks old) and F0(+) HLA-A11.1/B2M(M-NSG) humanized mice (male, 11 weeks old), and analyzed by flow cytometry with anti-HLA-ABC, anti-mH2D, anti-mB2M, and anti-hB2M. 

Abbr. WT, wild type.


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