Nkx2-1-CreERT2
品系全名
C57BL/6JSmo-Nkx2-1em1(CreERT2-pA)Smoc
目录号
NM-KI-200123
品系状态
活体
基因信息
基因名
Nkx2-1
品系描述
验证数据
图 1 Tamoxifen诱导后，Nkx2-1CreERT2/+; Rosa26tdTomato/+ 小鼠肺上皮细胞中tdTomato表达情况。
经Tamoxifen诱导后，Nkx2-1CreERT2/+; Rosa26tdTomato/+ 双转基因鼠，可在小鼠某些支气管和肺泡的上皮细胞中表达tdTomato。
图 2 Tamoxifen 诱导后，Nkx2-1CreERT2/+; Rosa26tdTomato/+ 小鼠各组织中tdTomato的表达情况。
CreERT2蛋白的活性在肺中被Tamoxifen依赖性诱导表达。此外，在垂体、视网膜、心脏、肝脏、胃、大肠、小肠、肾脏和胰腺等中都没有检测到tdTomato的表达。
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