Pgr-Cre

品系全名

C57BL/6JSmo-Pgrem1(iCre-WPRE-pA)Smoc

目录号

NM-KI-200117

品系状态

活体

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基因信息

基因名
Pgr

品系描述

将iCre-WPRE-pA插入到小鼠Pgr基因起始密码子处。
应用领域:Cre工具鼠,孕激素受体表达的细胞

验证数据

Pgr-(iCre)-1.png

Figure 1: PgriCre/+; Rosa26tdTomato/+ 小鼠脑部和雌性生殖系统中tdTomato的表达情况。

PgriCre/+; Rosa26tdTomato/+ 双转基因鼠,可在小鼠脑部及雌性生殖系统中表达tdTomato。证明Pgr-(iCre)小鼠可以成为实现Pgr阳性细胞特异性敲除或表达的工具鼠。

Pgr-(iCre)-2.png

Figure 2: PgriCre/+; Rosa26tdTomato/+ 小鼠各组织中tdTomato的表达情况。



发表文献 2篇

1. Endometrial stromal cell-derived TMAO sustains decidualization to prevent recurrent spontaneous abortion
发表年份:2026 来源杂志:Cell Metabolism

2. METTL3 is essential for normal progesterone signaling during embryo implantation via m6A-mediated translation control of progesterone receptor
发表年份:2023 来源杂志:PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

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