Cd79a-2A-Cre

品系全名

C57BL/6JSmo-Cd79aem(2A-Cre)Smoc

目录号

NM-KI-220089

品系状态

精子冻存

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基因信息

基因名
CD79a

品系描述

将2A-Cre插入到小鼠Cd79a基因终止密码子处。
应用领域:Cre工具鼠

验证数据

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Fig1. Cre mediated recombination in kidney of Cd79aCre/+; Rosa26tdTomato/+ mouse. 

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Fig2. Detection of tdTomato(red) in various tissues of Cd79aCre/+; Rosa26tdTomato/+ mouse. 

Tissues expressing tdTomato: stomach, salivary gland, adrenal gland, kidney, pancreas, large intestine, small intestine, spleen, genitalia, thymus, pituitary gland. Low expression in tissues: brain, lung, skin. Non-expressing tissues: heart, eye, liver, brown fat, spinal cord, muscle.  (9.6-weeks old, female) (For more detailed information please contact our technical advisor.) 

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Fig3. Detection of tdTomato expression in CD19+CD79a+ cells of spleen and peripheral blood by FACS.

Leukocytes were collected from HE Cd79a-2A-Cre mice (male, 16 weeks old) and HE/HE R26-CAG-LSL-tdTomato/Cd79a-2A-Cre mice (male, 4 weeks old), and analyzed by flow cytometry with anti-mCD79a. 

Abbr. HE, Heterozygote; WT, wild type.

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Fig4. Detection of tdTomato expression in CD19- cells of spleen and peripheral blood by FACS.

Leukocytes were collected from HE Cd79a-2A-Cre mice (male, 16 weeks old) and HE/HE R26-CAG-LSL-tdTomato/Cd79a-2A-Cre mice (male, 4 weeks old), and analyzed by flow cytometry with anti-mCD79a. 

Abbr. HE, Heterozygote; WT, wild type.


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