Our Credentials
Listed on the SSE Star Market, stock code 688265
R&D base for animal models of disease (biotechnology field) under the "863" program directed by the Ministry of Science and Technology
Shanghai Professional Technical Service Platform for Animal Models
Shanghai Professional Technical Service Platform for Comparative Medicine
Shanghai Engineering and Technological Research Center for Animal Models
Shanghai High and New Technology Enterprise (HNTE)
Shanghai Science and Technology Little Giant Enterprise
AAALAC accreditation
Download the Laboratory Animal Production License
Download the Laboratory Animal Usage License
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热门文章
Cre-ERT2在无Tamoxifen诱导的情况下,在细胞质内处于无活性状态;当Tamoxifen诱导后,Tamoxifen的代谢产物4-OHT(雌激素类似物)与ERT结合,可使Cre-ERT2进核发挥Cre重组酶活性。
查看你一定听说过Cre-lox重组系统,无论你是否直接进行过基因操作。由于Cre-lox系统具有操作简单、重组率高的优点,如今已经成为体内外遗传操作的强有力工具。利用Cre-lox系统,可以在特定细胞、组织或整个生物体,甚至在特定时间点敲除或表达某个基因,实现对特定基因的时空特异性操作,这对基因功能的研究和人类疾病动物模型的建立都具有深刻影响。
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