Epcam-2A-CreERT2
品系全名
C57BL/6JSmo-Epcamem1(2A-CreERT2)Smoc
目录号
NM-KI-00084
品系状态
胚胎冻存
基因信息
基因名
Epcam
品系描述
验证数据
图1 免疫荧光检测Epcam-CreERT2+/-; Rosa26 tdTomato+/-小鼠肾脏上皮细胞EPCAM与RFP （tdTomato）的共定位情况。
结果显示：成年小鼠经Tamoxifen诱导后，肾脏EPCAM阳性细胞的胞浆内有tdTomato的表达，证明Epcam-CreERT2+/-小鼠中CreERT2在肾脏中的表达类型符合预期。
图2 免疫荧光检测Epcam-CreERT2+/-; Rosa26 tdTomato+/-小鼠肝脏上皮细胞EPCAM与RFP （tdTomato）的共定位情况。
结果显示：成年小鼠经Tamoxifen诱导后，肝脏EPCAM阳性细胞的胞浆内有tdTomato的表达，证明Epcam-CreERT2+/-小鼠中CreERT2在肝脏中的表达类型符合预期。
图3 荧光显微镜检测Epcam-CreERT2+/-; Rosa26 tdTomato+/- 小鼠小肠上皮细胞RFP（ Tomato ）的表达。
结果显示：成年小鼠经Tamoxifen诱导后，小肠上皮细胞的胞浆内有tdTomato的表达，证明Epcam-CreERT2+/-小鼠中CreERT2在小肠中的表达类型符合预期。
图4 荧光显微镜检测Epcam-CreERT2+/-; Rosa26 tdTomato+/- 小鼠大肠上皮细胞RFP（ Tomato ）的表达。
结果显示：成年小鼠经Tamoxifen诱导后，大肠上皮细胞的胞浆内有tdTomato的表达，证明Epcam-CreERT2+/-小鼠中CreERT2在大肠中的表达类型符合预期。
你也可能感兴趣
Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute
On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.
查看Workshop：Progress and Advances in Preclinical immuno-Oncology Research
SMOC’s Annual Progress and Advances in Preclinical immuno-Oncology Research: The workshop is designed as a forum for ideas and opinions exchange on how to decrease the rate of clinical failures in oncology and immuno-oncology.
查看Customizing Mouse Models: Delivering in 100 Days to Speed Up Your Research!
At GenoBioTX, we understand that the lengthy wait times for gene-modified mouse models can hinder your research progress. Traditional methods often require 6-9 months, leading to delays and increased costs. That’s why we’re thrilled to introduce our innovative service designed to streamline this process and deliver results faster.
查看
