hCCL1

品系全名

C57BL/6JSmo-Ccl1tm2(hCCL1)/Smoc

目录号

NM-HU-2000074

品系状态

胚胎冻存

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基因信息

基因名
Ccl1

品系描述

通过同源重组,将小鼠Ccl1基因进行人源化修饰。
应用领域:免疫治疗;药物筛选

验证数据

image.png

Fig.1 Detection of CCL1 expression in thymus by RT-PCR. 

Wild type: only one band at 197 bp with primers F1/R1(mCcl1);

Homozygous: only one band at 194 bp with primers F2/R2(hCCL1).

Abbr. M, DNA marker; HO, homozygous; WT, wild type.

image.png

Fig.2 Detection of hCCL1 and mCCL1 expression in serum by ELISA (6-8wks, female, n=3). 

Abbr. HO, homozygous; WT, wild type.

Note. hCCL1 and C57BL/6 mice were i.p. injected with con.A for 3h.


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