Ascl1-CreERT2
品系全名
C57BL/6JSmo-Ascl1em1(CreERT2-Wpre-pA)Smoc
目录号
NM-KI-200207
品系状态
活体
基因信息
基因名
Ascl1
品系描述
验证数据
图 1 Ascl1CreERT2/+; Rosa26tdTomato/+ 小鼠脑部海马体中tdTomato的表达情况。
经Tamoxifen诱导后， Ascl1CreERT2/+; Rosa26tdTomato/+ 双转基因鼠，可在小鼠海马体齿状回颗粒细胞层(GCL)和分子层(ML)中检测到tdTomato的表达。未经Tamoxifen处理时，在海马体分子层可见tdTomato漏表达。
图 2 Ascl1CreERT2/+; Rosa26tdTomato/+ 小鼠侧脑室中tdTomato的表达情况。
经Tamoxifen诱导后， Ascl1CreERT2/+; Rosa26tdTomato/+ 双转基因鼠，可在小鼠侧脑室下区(SVZ)检测到tdTomato的表达。
图 3 Ascl1CreERT2/+; Rosa26tdTomato/+ 小鼠各组织中tdTomato的表达情况。Tamoxifen诱导后，tdTomato的表达可在海马和侧脑室部分细胞中表达。此外，可在胸腺、胃和小肠粘膜下层中检测到tdTomato的表达，而在颌下腺、视网膜、肺、棕色脂肪、肾、肌肉和脾脏中检测不到。（更多详细信息请联系我司技术顾问。）
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