Ly6a-2A-Cre

品系全名

C57BL/6JSmo-Ly6aem1(2A-iCre)Smoc

目录号

NM-KI-190028

品系状态

精子冻存

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基因信息

基因名
Ly6a

品系描述

将2A-iCre共表达结构插入到小鼠Ly6a基因终止密码子处。
应用领域:Cre工具鼠

验证数据

ly6a-1.png

Fig1.荧光检测 Ly6a-iCre+/- ; R26-tdTomato+/-  小鼠心脏中 tdTomato 的表达。

Ly6a-iCre 小鼠与 R26-tdTomato 小鼠进行交配,取心脏组织进行荧光显微镜拍照。实验结果显示 Ly6a-iCre 小鼠在心脏中表达较强。

ly6a-2.png

Fig2. 荧光检测 Ly6a-iCre 小鼠心脏中 tdTomato 的表达情况。

取 Ly6a-iCre 小鼠的心脏组织进行荧光检测,结果发现心脏中 tdTomato 的表达较强。

ly6a-3.png

Fig3.荧光检测 Ly6a-iCre+/- ; R26-tdTomato+/- 小鼠肾脏中 tdTomato 的表达。


Ly6a-iCre 小鼠与 R26-tdTomato 小鼠进行交配,取肾脏组织进行荧光显微镜拍照。实验结果显示 Ly6a-iCre 小鼠在肾脏中表达较强。

ly6a-4.png

Fig4. 荧光检测 Ly6a-iCre 小鼠肾脏中 tdTomato 的表达情况。

取 Ly6a-iCre 小鼠的肾脏组织进行荧光检测,结果发现肾脏中 tdTomato 的表达较强。




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