Slc17a7-IRES-Cre

品系全名

C57BL/6Smoc-Slc17a7em1(IRES2-iCre)Smoc

目录号

NM-KI-200086

品系状态

活体

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基因信息

基因名
Slc17a7

基因曾用名

Vglut1; AI851913; 2900052E22Rik

染色体位置

7

NCBI ID

72961

MGI ID

1920211

Ensembl ID

ENSMUSG00000070570

Pubmed

Slc17a7

人类同源基因

SLC17A7

品系描述

A IRES2-iCre expression cassette was knocked into the Slc17a7 gene stop codon site.
应用领域：Cre recombinase tool; Slc17a7(Sodium dependent Inorganic Phosphate cotransporter) is also known as Vglut1(Glutamate transporter). When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in cells expressing Slc17a7. This strain may be useful for studying glutamatergic synaptic vesicle trafficking and vesicle-bound, sodium-dependent phosphate transportation.

验证数据

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Fig. 1 Cre-mediated recombination in the brain of Slc17a7Cre/+; Rosa26tdTomato/+ mouse. TdTomato(red) is widely expressed in the brain of Slc17a7Cre/+; Rosa26tdTomato/+ mouse.

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Fig. 2 Detection of tdTomato(red) in various tissues of Slc17a7Cre/+; Rosa26tdTomato/+ mice. Cre mediated recombination can be detected in the brain, pituitary gland, eyes, heart, skin and colon. TdTomato can also be detected in individual cells of the lung, liver, stomach, submandibular gland, brown fat, muscle, spleen, thymus, small intestine, pancreas, kidney and epididymis. (For more detailed information please contact our technical advisor.)


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