Zbtb46-2A-CreERT2

品系全名

C57BL/6Smoc-Zbtb46em1(2A-CreERT2-WPRE-pA)Smoc

目录号

NM-KI-18021

品系状态

胚胎冻存

导出PDF

基因信息

基因名
Zbtb46

基因曾用名

BZEL; Btbd4; 2610019F01Rik; 4933406L05Rik

NCBI ID

72147

MGI ID

1919397

Ensembl ID

ENSMUSG00000027583

Pubmed

Zbtb46

人类同源基因

ZBTB46

品系描述

A 2A-CreERT2-WPRE-pA coexpression cassette is inserted befor the stop codon of mouse Zbtb46 gene via homologous recombination to establish a tamoxifen inducible Zbtb46-CreERT2 tool stain. This strain can be used to knockout target gene in Zbtb46+ cells after tamoxifen treatment when crossed with mice which carry loxp sites flanking target gene.
应用领域：Cre recombinase tool

验证数据

image.png

Fig 1. Cre-mediated recombination in spleen of Zbtb46CreERT2/+; Rosa26tdTomato/+ mice.

image.png

Fig 2. Detection of tdTomato (red) in various tissues of Zbtb46CreERT2/+; Rosa26tdTomato/+. Expression tissues include: liver, salivary gland, pituitary gland, adrenal gland, kidney, pancreas, spleen, testis, thymus. A few cells expressed in cerebellum, spinal cord, heart, brown fat, small intestine, colon, muscle, skin. (6.5-8 weeks old, male) (For more detailed information please contact our technical advisor.) 

你也可能感兴趣

Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute

On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.

查看
Customizing Mouse Models: Delivering in 100 Days to Speed Up Your Research!

At GenoBioTX, we understand that the lengthy wait times for gene-modified mouse models can hinder your research progress. Traditional methods often require 6-9 months, leading to delays and increased costs. That’s why we’re thrilled to introduce our innovative service designed to streamline this process and deliver results faster.

查看