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Models

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Foxp3-IRES-Luc-2A-tdTomato

品系名:C57BL/6Smoc-Foxp3em1(IRES-Luci-2A-tdTomato)Smoc
品系状态:胚胎冻存 | 目录号:NM-KI-200065

A IRES-luci-2A-tdTomato expression cassette was knocked into the Foxp3 gene stop codon site.

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Il7-Luc-2A-EGFP

品系名:C57BL/6Smoc-Il7em1(Luc-eGFP)Smoc
品系状态:胚胎冻存 | 目录号:NM-KI-00092

A Luciferase-2a-egfp-polyA cassette was inserted at ATG site of mouse Il7 gene.

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Wt1-CreERT2

品系名:C57BL/6Smoc-Wt1em1(CreERT2-WPRE-pA)Smoc
品系状态:活体 | 目录号:NM-KI-200127
验证数据:有

A CreERT2-WPRE-pA expression cassette was knocked into the Wt1 gene start codon site.

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hIL1RAP

品系名:C57BL/6Smoc-Il1raptm3(hIL1RAP)Smoc
品系状态:活体 | 目录号:NM-HU-2000070
验证数据:有

The endogenous mouse Il1rap gene was replaced by human IL1RAP gene.

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hSIRPA(2)/hCD47/hCTLA-4

品系名:C57BL/6Smoc-Sirpatm2(hSIRPA)Cd47tm1(hCD47)Ctla4tm1(hCTLA4) Smoc
品系状态:胚胎冻存 | 目录号:NM-HU-210368

hCTLA4(NM-HU-00014) was crossed with hSIRPA(2)/hCD47(NM-HU-2000111)to generate hSIRPA(2)/hCD47/hCTLA4 mice

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R26-LNL-PB

品系名:C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LNL-PB-V5)Smoc
品系状态:精子冻存 | 目录号:NM-KI-00065

These mice harbor a loxP-flanked STOP cassette preventing transcription of a CAG promoter-driven piggyBac transposase. The targeted mutation was inserted into the Gt(ROSA)26Sor locus by homologous recombination. PiggyBac transposase is expressed when bred to mice that express Cre recombinase.

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hNECTIN4

品系名:C57BL/6Smoc-Nectin4tm1(hNECTIN4)Smoc
品系状态:胚胎冻存 | 目录号:NM-HU-210016
验证数据:有

The endogenous mice Nectin4 gene was replaced by human NECTIN4 gene.

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hCXCL13

品系名:C57BL/6Smoc-Cxcl13tm1(hCXCL13)Smoc
品系状态:胚胎冻存 | 目录号:NM-HU-225079
验证数据:有

The endogenous mouse Cxcl13 gene was replaced by human CXCL13 gene.

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Il33-KO(2)

品系名:C57BL/6Smoc-Il33em2Smoc
品系状态:活体 | 目录号:NM-KO-190436
验证数据:有

Il33-KO(2) mice(Stock No.NM-KO-190436) carry a knockout allele derived from the targeted deletion of exon 3-7. While Il33-KO mice(Stock No.NM-KO-00099) have been pulled from shelves for some reasons and Il33-KO(3) mice(Stock No.NM-KO-210206) carrying the exon 2 deletion.

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R26-CAG-EGFP(2)

品系名:C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-EGFP-WPRE-polyA)Smoc
品系状态:精子冻存 | 目录号:NM-KI-190089

These mice harbor a CAG-EGFP-WPRE-polyA cassette in the Rosa26 locus.1 generated by homologous recombination. While R26-CAG-EGFP(Stock No.NM-KI-190088) and R26-CAG-EGFP(3)(Stock No.NM-KI-190090) function similarly to R26-CAG-EGFP(2) mice,for more detailed information please contact our technical advisor.

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