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Models

为您找到相关结果约42,164个
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C57BL/6

品系名:C57BL/6Smoc
品系状态:活体 | 目录号:SM-001
验证数据:有

C57BL/6 mice have a high reproductive capacity, a long life span, and a low tumor susceptibility. Male mice are aggressive and fight frequently. Diet can cause obesity, type II diabetes, and atherosclerosis in these mice. The C57BL/6 mouse is the first to have its entire genome sequenced. It is the most extensively used inbred mouse strain as a genetic basis for congenic and mutant mice. It is also used in genetics, metabolism, immunology, neurology, behavioral research, pharmacodynamics, and medication safety evaluation.

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Nnt-Flox(C57BL/6N)

品系名:C57BL/6NSmoc-Nntem1(flox)Smoc
品系状态:活体 | 目录号:NM-CKO-241631

These strains carry loxP sites flanking exon 6 of Nnt gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Nnt gene.

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Nnt-KO(C57BL/6NSmoc)

品系名:C57BL/6NSmoc-Nntem2Smoc
品系状态:精子冻存 | 目录号:NM-KO-251159

The exon 6 of Nnt gene was deleted to generate Nnt knockout mouse.

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Pnlip-T221M(C57BL/6N)

品系名:C57BL/6NSmoc-Pnlipem2(T221M)Smoc
品系状态:在研 | 目录号:NM-KI-253565

These mice carry a T221M mutation of Pnlip gene.

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hCD3EDG/hCD19/hCD38(C57BL/6Smoc)

品系名:C57BL/6Smoc-Cd3etm1(hCD3E)Cd3dtm1(hCD3D)Cd3gtm1(hCD3G)Cd19em1(hCD19) /Cd38em2(CD38)Smoc
品系状态:在研 | 目录号:NM-XA-252817

The hCD3EDG/hCD19 (NM-HU-220109) was crossed with hCD38(2)(NM-HU-190059) to generate hCD3EDG/hCD19/hCD38(2) mice.

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Plp1-Flox

品系名:C57BL/6Smoc-Plp1em1(flox)Smoc
品系状态:胚胎冻存 | 目录号:NM-CKO-200072

These mice carry loxP sites flanking exon 3 of Plp1 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Plp1 gene.

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hPD-1

品系名:C57BL/6Smoc-Pdcd1tm1(hPDCD1) /Smoc
品系状态:活体 | 目录号:NM-HU-00015
验证数据:有

The endogenous mouse Pdcd1 gene was replaced by human PDCD1(PD-1) gene .

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CAG-hACE2-IRES-Luc-Tg

品系名:C57BL/6Smoc-Tgtn(CAG-human ACE2-IRES-Luciferase-WPRE-polyA)Smoc
品系状态:活体 | 目录号:NM-TG-200002
验证数据:有

The transgene is composed of a CAG-human ACE2-IRES-Luciferase-WPRE-polyA expression cassette under the control of CAG promter.

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hPD-L1

品系名:C57BL/6Smoc-Cd274tm1(hPD-L1)Smoc
品系状态:活体 | 目录号:NM-HU-00062
验证数据:有

The endogenous mouse Cd274(also known as PD-L1) gene was replaced by human PD-L1 gene . While hPD-L1(2)(Stock No.NM-HU-190039) mice function similarly to hPD-L1 mice,for more detailed information please contact our technical advisor.

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R26-CAG-LSL-RSR-tdTomato-2A-DTR

品系名:C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-RSR-tdTomato-2A-DTR)Smoc
品系状态:活体 | 目录号:NM-KI-190086
验证数据:有

These mice harbor a CAG-LSL-RSR-tdTomato-2A-DTR cassette in the Rosa26 locus generated by homologous recombination.

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