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R26-SA-BirA

品系名：B6;129S-Gt(ROSA)26Sortm1(SA-BirA-V5)Smoc
品系状态：胚胎冻存 | 目录号：NM-KI-00085
验证数据：有

A SA-BirA-polyA expression cassette was knocked in mouse Rosa26 loci . Heterozygous knockin mice developed normally.

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Wt1-CreERT2

品系名：C57BL/6Smoc-Wt1em1(CreERT2-WPRE-pA)Smoc
品系状态：活体 | 目录号：NM-KI-200127
验证数据：有

A CreERT2-WPRE-pA expression cassette was knocked into the Wt1 gene start codon site.

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R26-LNL-PB

品系名：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LNL-PB-V5)Smoc
品系状态：精子冻存 | 目录号：NM-KI-00065

These mice harbor a loxP-flanked STOP cassette preventing transcription of a CAG promoter-driven piggyBac transposase. The targeted mutation was inserted into the Gt(ROSA)26Sor locus by homologous recombination. PiggyBac transposase is expressed when bred to mice that express Cre recombinase.

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R26-CAG-EGFP(2)

品系名：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-EGFP-WPRE-polyA)Smoc
品系状态：精子冻存 | 目录号：NM-KI-190089

These mice harbor a CAG-EGFP-WPRE-polyA cassette in the Rosa26 locus.1 generated by homologous recombination. While R26-CAG-EGFP(Stock No.NM-KI-190088) and R26-CAG-EGFP(3)(Stock No.NM-KI-190090) function similarly to R26-CAG-EGFP(2) mice,for more detailed information please contact our technical advisor.

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Nkx2-1-CreERT2

品系名：C57BL/6Smoc-Nkx2-1em1(CreERT2-pA)Smoc
品系状态：活体 | 目录号：NM-KI-200123
验证数据：有

A CreERT2-pA expression cassette was knocked into the Nkx2-1 gene start codon site. Nkx2-1, a key molecule in lung development, is expressed in adult bronchial and alveolar type Ⅱ epithelial cells. Besides, Nkx2-1 expression as a prognostic marker is also been applied to lung cancer research including lung adenocarcinoma.

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R26-hCD46-IRES-tdTomato

品系名：C57BL/6Smoc-Gt(ROSA)26Sortm1(SA-hCD46-IRES-tdTomato-polyA)Smoc
品系状态：胚胎冻存 | 目录号：NM-KI-190087
验证数据：有

These mice harbor a SA-human CD46-IRES-tdTomato-polyA cassette in the Rosa26 locus generated by homologous recombination.

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hPD-1/hVISTA

品系名：C57BL/6Smoc-Visrtm1(hVSIR)Pdcd1tm1(hPDCD1)Smoc
品系状态：胚胎冻存 | 目录号：NM-HU-2000092

hPD-1(NM-HU-00015) was crossed with hSIRPA(2) (NM-HU-18015) to generate hPD-1/hVISTA.

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H11-CAG-ddCre

品系名：C57BL/6Smoc-Igs2em1(CAG-ddCre-V5-polyA)Smoc
品系状态：胚胎冻存 | 目录号：NM-KI-00086

These H11-(CAG-ddCre-V5-polyA) mice are established by knocking CAG-LSL-ddCre-V5-polyA conditional expression cassette in mouse H11 loci.

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Calb1-2A-GFPCre

品系名：C57BL/6Smoc-Calb1em1(2A-EGFP-Cre)Smoc
品系状态：精子冻存 | 目录号：NM-KI-200141
验证数据：有

A 2A-EGFP-Cre expression cassette was knocked into the Calb1 gene stop codon site. Calb1 is highly expressed in the brain. When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in cells expressing Cre. This strain is useful in studying many neurobehavioral diseases such as spatial learning and circadian rhythm interference. It has been reported that the incidence of many diseases may be different between genders.

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Tnnt2-dCreERT2

品系名：C57BL/6Smoc-Tnnt2em1(rox-CreERT2-wpre-polyA-rox-tdTomato-wpre-polyA)Smoc
品系状态：活体 | 目录号：NM-KI-200015

A rox-CreERT2-wpre-polyA-rox-tdTomato-wpre-polyA expression cassette was knocked into the Tnnt2 gene start codon site.

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