品系名:C57BL/6Smoc-Ace2em2(2A-CreERT2-WPRE-polyA)Smoc
品系状态:精子冻存 | 目录号:NM-KI-200187
验证数据:有
A 2A-CreERT2-WPRE-polyA expression cassette was knocked into the Ace2 gene stop codon site.
Ace2 encodes angiotensin I converting enzyme 2. When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in cells expressing Cre. This strain is useful for studying lung injury and kidney disease caused by SARS coronavirus infection.