Tert-CreERT2-2A-EGFP

品系全名

C57BL/6Smoc-Tertem1(CreERT2-2A-GFP-WPRE-PA)Smoc

目录号

NM-KI-18037

品系状态

胚胎冻存

导出PDF

基因信息

基因名
Tert

品系描述

在Tert基因起始密码子位点定点敲入CreERT2-2A-GFP-WPRE-PA表达框。

应用领域:Cre工具鼠

验证数据

image.png

Fig1. CreERT2 mediated recombination in small intestine of TertCreERT2-EGFP/+;Rosa26tdTomato/+ mouse.

image.png

Fig2. Detection of EGFP(green) and tdTomato(red) in various tissues of TertCreERT2-EGFP/+;Rosa26tdTomato/+ mouse. Expression tissues include: small intestine, lung, liver, salivary gland, kidney, pancreas. A few cells expressed in brain, stomach, colon, spleen, skin, thymus, ovary. Tissues that unexpressed include eye, heart, brown fat. No significant EGFP positive signal was detected. (6.5-months old, female) (For more detailed information please contact our technical advisor.) 



你也可能感兴趣

Tamoxifen诱导Cre-ERT2小鼠 使用指南

Cre-ERT2在无Tamoxifen诱导的情况下,在细胞质内处于无活性状态;当Tamoxifen诱导后,Tamoxifen的代谢产物4-OHT(雌激素类似物)与ERT结合,可使Cre-ERT2进核发挥Cre重组酶活性。

查看
【小鼠大学问】基因工程小鼠的命名规则

常见的基因工程小鼠可以分为两种命名方式,包括基因定点修饰的小鼠命名,比如:敲除、敲入、点突变等等,和随机转基因的小鼠命名。

查看