R26-(CAG-LSL-dCas9-VPR-IRES-EGFP-WPRE-pA)


Strain Information

Strain Name

C57BL/6J-Gt(ROSA)26Sorem1(CAG-LSL-dCas9-VPR-IRES-EGFP-WPRE-pA)

Cat. NO.

NM-KI-18004

Gene Symbol

dCas9

Gene Synonyms

Human Ortholog

Ensembl ID

MGI ID

NCBI ID


Description

These mice harbor a CAG-LSL-dCas9-VPR(VP64-p65-Rta)-eGFP-pA conditional expression cassette in mouse Rosa26 loci by CRISPR/Cas mediated homologous recombination. This strain can be used in CRISPR mediated target gene transcriptional activation (CRISPRa).

Research application

gene regulation tool,CRISPRa

Status

Availability

Embryo cryopreservation


Related Articles

Milestones

Our vision is to provide researchers all over the world with comprehensive, convenient and professional animal model services to facilitate a simplified and highly-efficient approach towards uncovering the mysteries of life.

查看
Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute

On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.

查看
Contact us Email Gene-editing proposal Gene-editing proposal Back to top Back to top