Aplnr-DreERT2


Strain Information

Strain Name

C57BL/6J-Aplnrem1(2A-DreERT2)Smoc

Cat. NO.

NM-KI-00132

Gene Symbol

Aplnr

Gene Synonyms

Agtrl1, apelin receptor, APJ, msr/apj

Human Ortholog

APLNR

Ensembl ID

MGI ID

NCBI ID


Description

A 2A-DreERT2-SV40polyA coexpression cassette is inserted befor the stop codon of mouse Aplnr gene via homologous recombination to establish a tamoxifen inducible Aplnr-DreERT2 tool stain. This strain can be used to knockout target gene in Aplnr+ cells after tamoxifen treatment when crossed with mice which carry rox sites flanking target gene.

Research application

recombinase tool

Status

Availability

Embryo cryopreservation


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Milestones

Our vision is to provide researchers all over the world with comprehensive, convenient and professional animal model services to facilitate a simplified and highly-efficient approach towards uncovering the mysteries of life.

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Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute

On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.

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