Nppa-rtTA


Strain Information

Strain Name

B6;129-Nppatm1(M2rtTA)Smoc

Cat. NO.

NM-KI-00127

Gene Symbol

Nppa

Gene Synonyms

Anf, ANP, atrial natriuretic peptide, natriuretic peptide precursor A, Pnd

Human Ortholog

NPPA

Ensembl ID

MGI ID

NCBI ID


Description

An M2rtTA-bGH-polyA expression cassette is inserted in Nppa gene via homologous recombination to establish a tetracycline-controlled Nppa-rtTA (tet-on) tool stain. When crossed with mice of which a target gene was driven by a TRE promoter, the target gene could be induced to express in Nppa+ cells after Dox administration.

Research application

tetracycline-controlled regulation tool

Status

Availability

Embryo cryopreservation


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Milestones

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